研究業績-2013|糖尿病 食事療法 治療 京大病院 栄養内科





研究業績

Suzuki, K., Harada, N., Yamane, S., Nakamura, Y., Nasteska, D., Sasaki, K., Joo, E., Shibue, K., Harada, T., Hamasaki, A., Toyoda, K., Nagashima, K., and Inagaki, N. Transcriptional regulatory factor X 6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high-fat diet-induced obesity. J. Biol. Chem. 288: 1929-1938, 2013.
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Harashima, S.-I., Fukushima, T., Sasaki, M., Nishi, Y., Fujimoto, S., Ogura, M., Yamane, S., Tanaka, D., Harada, N., Hamasaki, A., Nagashima, K., Nakahigashi, Y., Seino, Y., and Inagaki, N. Self-monitoring of blood glucose (SMBG) improves glycemic control in oral hypoglycemic agents (OHA)-treated type 2 diabetes (SMBG-OHA Study) Diabetes Metab. Res. Rev. 29: 77-84, 2013.
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Saito, M., Hayakawa, A., Inagaki, N., and Matsuoka, H. Development of novel cell lines of diabetic dysfunction model fit for cell-based screening tests of medicinal materials. Cytotechnology 65: 105-118, 2013.
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Joo, E., Yamane, S., Hamasaki, A., Harada, N., Matsunaga, T., Muraoka, A., Suzuki, K., Nasteska, D., Fukushima, T., Hayashi, T., Tsuji, H., Shide, K., Tsuda, K., and Inagaki, N. Enteral supplement enriched with glutamine, fiber, and oligosaccharide attenuates experimental colitis in mice. Nutrition, 29:549-555, 2013.
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Araki, E., Kawamori, R., Inagaki, N., Watada, H., Hayashi, N., Horie, Y., Sarashina, A., Thiemann, S., von Eynatten, M., Woerle, H. J. Long-term safety of linagliptin in Japanese patients with type 2 diabetes. Diabetes Obes. Metab. 15: 364-371, 2013.
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Harashima, S.-I., Tanaka, D., Yamane, S., Ogura, M., Fujita, Y., Murata, Y., Seike, M., Koizumi, T., Aono, M., and Inagaki, N. Efficacy and safety of switching from basal insulin to sitagliptin in Japanese type 2 diabetes patients. Horm. Metab. Res., 45:231-238,2013.
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Tanaka, D., Nagashima, K., Sasaki, M., Funakoshi, S., Kondo, Y., Yasuda, K., Koizumi, A., and Inagaki, N. Exome sequencing identifies a new candidate mutation for susceptibility to diabetes in a family with highly aggregated type 2 diabetes. Mol. Genet. Metab.109: 112-117, 2013.
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Overbeck, T. R., Hupfeld, T., Krause, D., Baldmann-Beushausen, R., Chapuy, B., Guldenzoph, B., Inagaki, N., Schondube, F. A., Danner, B., Truemper, L., and Wulf, G. G. Intracellular ABC transporter A3 (ABCA3) is expressed in lung cancer cells and moldulates susceptibility to cisplatin and paclitaxel. Oncology 84: 362-370, 2013

Takagi, T., Furuta, H., Miyawaki, M., Nagashima, K., Shimada, T., Doi, A., Matsuno, S., Tanaka, D., Nishi, M., Sasaki, H., Inagaki, N., Yoshikawa, N., Nanjo, K., and Akamizu, T. Clinical and functional characterization of a novel ABCC8 gene mutation associated with permanent neonatal diabetes mellitus. J. Diabetes Invest., in press.

Ikeda, K., Fujimoto, S., Goto, M., Yamada, C., Hamasaki, A., Ida, M., Nagashima, K., Shide, K. Kawamura, T., and Inagaki, N. A new equation to estimate basal energy expenditure of patients with diabetes. Clin. Nutr., in press
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Sasaki, M., Fujimoto, S., Sato, Y., Nishi, Y., Mukai, E., Yamano, G., Sato, H., Tahara, Y., Ogura, K., Nagashima, K., and Inagaki, N. Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproduction. Diabetes, in press.
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Inagaki, N., Watada, H., Murai, M., Kagimura, T., Gong, Y., Patel, S, and Woerle, H.-J. Linagliptin provides effective, well tolerated add-on therapy to pre-exisisting oral antibiotic therapy, over 1 year, in Japanese patients with type 2 diabetes. Diabetes Obes. Metab. in press.
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Abudukadier, A., Fujita, Y., Obara, A., Ohashi, A., Fukushima, T., Sato, Y., Ogura, M., Nakamura Y., Fujimoto, S., Hosokawa, M., Hasegawa, H., and Inagaki, N. Tetrahydrobiopterin lowers fasting blood glucose levels by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice. Diabetes, in press.
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